Molecular Diffusion on Surfaces We make extensive use of fluorescence recovery after photobleaching (FRAP) to measure the diffusive properties of lipids and proteins in membranes.
Curved Lipid Membranes Lipid bilayer membranes readily self-assemble on silica particles. Our group uses these spherical supported lipid bilayers to investigate molecular partitioning and curvature-dependent biomolecular interactions.
Soft Matter Sensing Our group uses quartz crystal microbalance with dissipation (QCM-D) sensing to investigate processes that occur on lipid bilayer membrane surfaces. QCM-D can measure tiny changes in mass (as small as picograms!) and structural properties (viscoelasticity) that result from vesicles rupturing and biomolecular interactions.
Dark and Spacy A microarray of sub-micron spherical supported lipid bilayers used to investigate lipid-protein interactions. Read more at this link: http://pubs.acs.org/doi/abs/10.1021/ac3014274
